You need to keep your office clean at any cost because it can have severe effect on your business. The unclean and unhygienic environment in the office can affect the health of people working for you.
If the office environment is dirty, people will not feel fully comfortable in the office environment so would not be able to put their best efforts. What is more, they will most often send you requests for sick leaves. Therefore, you will never be able to achieve your business goals despite you replace people to improve the quality of the work.